At the age of 38, as long as Federer played, I wanted to play for as long

At the age of 38, as long as Federer played, I wanted to play for as long
Xiao Weishang has no timetable for retirement, and her goal is “not to retire, I will not retire.”Figure / Osports Williams Nationality: American Birthday: September 26, 1981 Height: 1.75 meters project: Tennis career: 1995 23 women’s singles Grand Slam champions, 14 women’s doubles Grand Slam champions, 5 year-end finals champions, 3 Olympic women’s doubles gold medals, 1 Olympic women’s singles gold medal women’s tennisOne week after the start of the new season, the biggest news was that Williams won the WTA Auckland Open championship.Although it is only one of the lowest-level tour champions, for 38-year-old Serena Williams, breaking the three-year championship shortage one week before the Australian Open is bound to be good news.In the past two years, Serena Williams returned to the Grand Slam without success.Next week in Melbourne, if Williams can win the championship, he will tie the best record in the history of Margaret Court.  The total prize money for breaking the 3-year championship in Auckland is only $ 250,000, which is the lowest level of the tour in the WTA event system.In 2017, Serena chose the Auckland Open as the Australian Open warm-up and eventually won the Australian Open with a pregnancy.This year, the 38-year-old Serena once again chose Auckland to warm up for the Australian Open.The difference is that this time together with her husband and daughter, Oakland became one of the few “mom players” in the tournament.  At the same time as the Auckland Open, there are also the Shenzhen Open with higher levels and bonuses, the Brisbane Open, and most of the TOP10 players have gone to two stations.The Oakland Open originally invited Anderscu and Serena two TOP10 players, but the former retired due to a knee injury.  This kind of point looks a little “water”, but for Wei Wei, every game is not easy to play. In the second round, he was almost upset by fellow McHall.Among the five games, the highest ranking of Serena’s opponents was Anisimova, ranked 25th, and Pegula, the final opponent, ranked only 82 in the world.  According to the previous, Williams participating in such a low-level event will be considered by fans as a “brush crown” itself.But if you understand the performance of Williams in the past two seasons, you will definitely not have this view.After the return of the maternity in 2018, Xiaowei scored five championships, all of which failed, and her last championship was the 2017 Australian Open.Facing Pegula, Serena played a straight back focus at the match point and shouted in the sky, releasing his depressed emotion for a long time.  ”I haven’t won the championship in a long time, I think you can see the expression of joy on my shoulder.This is really important to me, I just want to build on it.This is just a small step towards the next goal.”Although it was only the lowest-level tour champion, it was extremely important for Serena.  Talking about the ups and downs of these two seasons, Xiaowei said that he must maintain a good mentality so that he can return to the top ranks of the tournament, “You must be your biggest cheerleader, especially when you feel like doing everythingNot right or all right, but when things cannot be resolved.”Xiaowei believes that whenever he has to learn to cheer for himself, this is a great motivation to continue moving forward.”  The prospect avoids the big seed and rushes to 24 crowns. The 2017 Australian Open women’s singles finals, Williams defeated his sister David, won the 23rd Grand Slam championship, and then surpassed 22 crowns Graf, ranking first in the history of the Open.In front of Xiaowei, only Margaret Court with 24 crowns remained.  In the nine majors before that, Williams reached the final seven times and took away five championships.Everyone thinks that it is only a matter of time before Weiwei equalizes Court.But every month, everyone knew that Xiaowei had won the Australian Open championship with her pregnancy, and she ended the 2017 season in advance.  At the beginning of 2018, Xiaowei returned after giving birth, and she has had four opportunities to tie up with Court in two years.In 2018 Wimbledon, the US Open women’s singles final, Xiaowei lost to Kobel one after another, Nasaka Osaka.At Wimbledon in 2019, the US Open women’s singles final, Serena lost to Halep and Andrescu.  In the two Wimbledon finals, Xiaowei lost to Kobel and Halep in the case of superior results.In the two US Open finals, Xiaowei’s opponents were the first to reach the Grand Slam: 21-year-old Naomi Osaka and 19-year-old Andrescu.Under almost all favorable external conditions, a small well known as the big heart repeatedly turned over.  After winning the championship in Auckland, Serena flew straight to Melbourne to prepare for the Australian Open starting next week. “I feel very well. I played a few good games here (Auckland). This is exactly what I need to prepare for the Australian Open.”In addition to gaining confidence, Williams also has the championship in Oakland, raising the world ranking from 10th to 9th.It looks like there is only one difference, but the meaning is very different.As Andlescu, ranked sixth, withdrew from the Australian Open due to injury, Xiaowei, ranked ninth, became the No. 8 seed in the women’s singles, which ensured that she would not encounter a big seed in the first four rounds.  Good seed signing made Xiaowei’s Australian Open trip look a bit too much, and tied up with Court again to see hope.”I lost two Grand Slam finals in 2019, which was very difficult for me.I’m almost there, I believe it can be done, which means a lot to me.”Xiaowei’s goal is very clear, that is, to tie the level and surpass the historical record,” I have had many opportunities, and there are opportunities in the future.”The anniversary of winning the championship spanned four times at the Oakland Open, and Williams won her 73rd singles title in her career, 21 years after she won her first career title in Paris in 1999.In this regard, Serena became the first player in the tennis world to cross the 1990s, 2000s, 10s and 20s and have tour champions.  In the Paris Indoors in 1999, Serena Williams, who was under 18, won his first personal championship and won the first Grand Slam championship at the US Open in the same year.”At that time, I thought I would retire when I was 28 or 29 years old.”Xiaowei did not expect to continue to be active in the tournament at the age of 38, and he has the opportunity to compete for a grand slam.  From 1995 to becoming a professional player, Xiaowei has been playing in the tennis world for 25 years, and has swept away generations of players. “Throughout my career, you will find that I have experienced several times in the women’s net and have fought against generations of players, I can win so many championships, really proud of myself.”In the new season, Xiaowei still maintains a good state, and there is not much drift in physical fitness.”In Oakland, she reached the finals in both singles and doubles.Last season, Xiaowei only participated in 8 races, which is the least number of TOP200 players, but the ranking is still stable in the top 10 in the world, indicating the game.  In the women ‘s tennis world, most people will lose a lot of competition after they turn 30.Graff retired at the age of 30, and Court insisted on retiring at the age of 35, but no grand slam after 31.After the US Open this year, Xiaowei will celebrate her 39th birthday, and she is still regarded as a Grand Slam hit.  ”I think I belong to a new generation of athletes. I am fortunate to have more comprehensive equipment, including suitable shoes and other conditions. I know how to take care of my body and feel that my body is younger than my actual age.”Xiaowei said that age is not a big problem for today’s players. Tennis, basketball and other athletes have a longer professional career, which was very rare a few years ago.Xiaowei couldn’t even play for as long as she could, but she specified a reference. “As long as Federer played (born in 1981 with Xiaowei), I want to play for as long as possible.””Author / Sauna, Night Net Sun Haiguang

[Can I eat sorbet during pregnancy]_Pregnancy_Can I eat

[Can I eat sorbet during pregnancy]_Pregnancy_Can I eat

Pregnant women should be particularly aware of their bodies. Their bodies are very fragile, so they have many dietary taboos. Such things as sorbet are not suitable for everyone, and some are not suitable for people.In view of this, it can cause a lot of problems, such as diarrhea, and some people say that pregnant women can eat sorbet, but deny this statement, can pregnant women eat sorbet?

You can eat ice cream during pregnancy, but it is recommended that pregnant women eat as little ice cream as possible.

Many doctors and experts will ask pregnant women not to eat too much cold, cold food during pregnancy.

Some people think that eating cold, cold foods such as jelly, watermelon, and ice cream can cause premature or even small births.

Studies have shown that eating ice cream in pregnant women will not cause premature or small births, but excessive consumption will definitely cause discomfort. After all, pregnancy is a special period.

Ice cream is mainly composed of 3 ingredients, a few of which account for 7%?
16%, sucrose 14%?
20%, protein 3%?
4%, ice cream contains feces mainly from milk and eggs, lipid lecithin can release choline, which is helpful to improve people’s memory.

Ice cream contains sugar, which is composed of lactose in milk and various fruit juices, fructose and sucrose in fruit pulp. Organic acids, tannins and various vitamins can provide the body with the necessary nutrients.

In addition to the above nutritional values, ice cream also contains milk or dairy products, eggs or egg products, sweeteners, flavoring agents, stabilizers and food colors as raw materials. Pregnant women should also consider these when eating ice cream.

Many people think that the germs of frozen food must be killed by low temperature, and it is safe to eat.

In fact, frozen foods such as ice cream may also contain germs, leading to the occurrence of “ice cream disease”.

In addition, pregnant women should prevent “cold drinking disease” and “refrigerator disease” in summer.

If you eat too much ice cream, you will experience abdominal distension, abdominal pain, irritability and other symptoms; the refrigerator is not a sterile box, some psychrophiles, molds are resistant to low temperature, and some refrigerators even have dysentery bacillus, which can cause abdominal pain, diarrhea and other acute inflammation, so pregnantIt is best for mothers to restrain their desire to eat ice cream and minimize the danger.

[Chiba tofu is harmful to the body]_harm_impact

[Chiba tofu is harmful to the body]_harm_impact

Tofu is a bean product made from beans. It has high nutritional value. Tofu was added by the Taiwanese in the later development to make Chiba tofu. Chiba tofu is more crispy and tender than ordinary tofu.It tastes better. Although Chiba Tofu has high nutritional value, it cannot be eaten every day. So what harm does Chiba Tofu have on the body?

Thousand-sheet tofu is a new vegetarian product that is widely popular in coastal cities on the mainland and northern regions.

It uses Taiwan’s latest tofu production process, refined with soybean flour and starch as the main materials. It is a new century cuisine of protein and protein. At the same time, it maintains the original tenderness of tofu, more unique Q strength and crispnessWith super-abundant soup absorbing ability, with modern cooking skills, you can make high-quality new fashion delicious dishes.

It can be fried, boiled, fried, fried, steamed, grilled, braised, hot pot, etc.

The raw materials are simple, but the display is exquisite, which shows the grade.

Tofu is hot and slippery and delicious.

Thousand-sheet tofu can be eaten in many ways, either as a stand-alone dish, as a main ingredient, auxiliary ingredient, or as a seasoning; it is suitable for a variety of cooking methods, can be steamed, stewed, fried, smoked, and cold-sold; it can be filled with a variety ofDishes, a variety of shapes, can be cold cuts, hot dishes, soups, hot pots, can be rolled into rolls, clips, pills, bags, etc. wrapped into a variety of flavors, not only the original flavor of beans, must be unique and uniqueTaste characteristics.

What is Chiba Tofu harmful to the human body? Chiba Tofu is produced from soybean protein powder and is not harmful to the human body.The nutritional ingredients that the human body normally needs, but because of the low trace, it will not grow meat when consumed. Therefore, it is now welcomed by consumers. What is Chiba Tofu harmful to the human body?Tofu provides rich calcium and magnesium for human beings. Calcium is an important element required in various physiological and biochemical metabolic processes of the human body. It can maintain the breakdown of cell membranes and participate in nerve and muscle activities. It is the main component of bones and teeth.Ingredients are the material basis for children’s growth and development, middle-aged and elderly prevention, and treatment of osteoporosis.

Eating 200 grams of old tofu can meet 1/3 of the calcium requirement of a day.

Magnesium can relax the tension of arterial blood vessels, help lower blood pressure, prevent cardiovascular and cerebrovascular diseases, and strengthen bones and teeth.

Soy products also contain phospholipids, isoflavones, and cholesterol, so tofu is a veritable health food.

2. Thousands of tofu contains a small amount of glucose and trace amounts, which is a low-energy food, which is also very important.

3. Thousand-sheet tofu contains vitamins, half a thousand-sheet tofu (about 150 grams) contains vitamin B1 as 0.

10-0.

15 mg; vitamin B2 is 0.

05——0.

06 mg; vitamin E is 0.

5-0.

9 mg; vitamin K is 18.

0-19.

5 mg; nicotinic acid and so on each time.

These are all essential vitamins for the human body.

4. Thousands of sheets of tofu contain minerals, and the remaining minerals of soybeans are contained in tofu, and some are added as coagulants in production.

Half a piece of tofu contains 65-180 mg of calcium; 47-66 mg of magnesium; and iron 1.

2——1.

4 mg; zinc 0.

8-0.

9 mg; potassium 210-225 mg.

There are also copper, phosphorus and so on.

5. What’s more important is that thousands of tofu contain many functional ingredients.

These functional ingredients are mainly linoleic acid, lecithin, isoflavones, choline, saponin, selenium, plasma proteases and the like.

6. The nutritional value of tofu is similar to that of milk. For people who cannot drink milk due to lactose intolerance, or do not eat meat and poultry for the purpose of controlling chronic diseases, tofu is the best substitute.

7, thousand pages of tofu is the best source of plant protein, so it has the reputation of “plant meat”.

The process of tofu is the process of extracting the protein in soybean and reconstituting and solidifying it.

So tofu contains a lot of protein, and half a tofu (about 150 grams) contains protein 7.

4-9.

9 grams, the protein in tofu is excellent protein, contains all kinds of 20 amino acids, including 9 essential amino acids required by the human body, and the content is balanced.

Thousands of tofu are rich in protein, trace amounts, and calcium and magnesium, so tofu is not only a good source of human protein, but also a good source of calcium and magnesium.

[Hang Frost Cashew Nuts]_Cashew Nuts_Home Practices_Production

[Hang Frost Cashew Nuts]_Cashew Nuts_Home Practices_Production

Crispy cashews are a common snack during the Chinese New Year. They are usually eaten during leisure time. The most popular food is cashew nuts with frost. When you eat, you need to prepare some sugar and cashew nuts.Some peanut oil and cashew nuts need to be fried until crispy, and finally sprinkled with white sugar to make it. The first ingredient is cashew nuts (400 grams).

Seasoning: caster sugar (150 g) peanut oil (10 g).

Process 1.

Put the wok on medium heat, inject peanut oil, add cold oil to cashew nuts. When the oil temperature is controlled at 40%, fry for 3 to 5 minutes. If the color of cashew nuts changes slightly, immediately remove the drained oil.

2.

On a frying pan tempering, add 20 grams of water and add sugar, slowly boil, turn milk off when it is milky white, add cashews, mix well, cool into a pan and fill the nuts with ice cream.

Practical materials: 300 grams of cashew, 1 orange seasoning: process 1.

Get ready for caster sugar, oranges, cashews 2.

Cut out some orange peels, not white parts, and chopped, don’t cut into 3 pieces.

First prepare a small pot of sugar water, 600 ml of water, 1 tablespoon of white sugar, blanch the cashew nuts with sugar water, allow the sugar to adhere to the surface of the cashew nuts to form a sugar coating, and then fry them.

Remove the cashews that have been blanched with sugar water, drain the water, and fry them in an oil pan. Medium-low temperature oil, slowly fry, fry for 10-15 minutes, until golden yellow.

Remove the fried cashew nuts. At this time, pour the orange peel into the cashew nuts and mix it a little. After the orange peel is preheated, the fragrance will soon come out.

Take another pot, add 2 tablespoons of water and 5 tablespoons of white sugar, slowly heat to dissolve the sugar, cook the bubbles, and when the bubbles become large and thick, add cashews, turn off the fire at the same time, and then stopStir fry so that each grain of cashew is covered with sugar. At the same time, the orange peel is also attached to the cashew with sugar, and the frosting is completed by decreasing the temperature.

Taiji shares (002368) quarterly report comments: third-quarter revenue accelerated growth Issuance of convertible bonds layout

Taiji shares (002368) quarterly report comments: third-quarter revenue accelerated growth Issuance of convertible bonds layout

Matters: The company announced the third quarter report of 2019, and achieved operating income of 45 in the first three quarters of 2019.

8.4 billion, an annual increase of 18.

02%, achieving net profit of 7618.

310,000 yuan, an annual increase of 9.

58%, EPS is 0.

1876 yuan.

Ping An’s perspective: The company’s third-quarter revenue accelerated growth: According to the company’s announcement, 北京桑拿洗浴保健 the company achieved operating income of 45 in the first three quarters of 2019.

84 ppm, an 18-year increase.

02%.

In terms of quarters, the company’s revenue growth rate in the first quarter, second quarter, and third quarter was 9 each year.

44%, 14.

34%, 32.

27%, the company’s third quarter revenue continued to accelerate growth and accelerated significantly, indicating that the company’s main business development situation is good.

In the first three quarters of 2019, the company achieved a net profit of 7618.

310,000 yuan, an increase of 9 in ten years.

58%, net profit attributable to mothers has steadily increased.

The company’s gross profit margin and period expense ratio increase every quarter, and the increase in research and development expenses increases: the company’s gross profit margin for the first three quarters of 2019 was 23.

89%, an increase of 2 a year.

92 units.

Company expenses during the first three quarters of 201921.

18%, an increase of 2 per year.

52 units.

Among them, the sales expense ratio increases by 1 every year.

One single, mainly due to market expansion and increased sales staff; management expense ratio (management expenses including research and development expenses) further increased 1.
.

The 51 singles are mainly due to the company’s continued increase in R & D investment and further increase in R & D expenses.

The company’s R & D expenses for the first three quarters of 2019 were 1.

2 ‰, an increase of 89 in ten years.

82%, the proportion of revenue from R & D expenses increased by about 1 average each year.

The issuance of convertible bonds includes cloud computing, self-controllable and other fields, and future development is expected: the company’s application for public issuance of convertible bonds was approved by the Securities and Futures Commission in September of the year, and the issuance has been completed.

The size of the funds raised from the issuance of convertible bonds is US $ 1 billion. After deducting the issuance costs, it is intended to be used for “Taiji’s independent and controllable key technology and product research and development and industrialization projects”, “Taiji cloud computing center and cloud service system construction projects”,”Taiji Industrial Internet Service Platform Construction Project”, “Supply Liquidity” and other four projects.

The implementation of the fundraising project will strengthen the company’s competition in the domestic cloud computing, autonomous and controllable, industrial Internet fields, help the company grasp the future development direction of the information technology industry, and realize the company’s strategic vision of “being the best digital service provider in China”Provide strong support.

Profit forecast and investment recommendations: According to the company’s 2019 third quarter report, we adjusted the company’s profit forecast for 2019-2021, and EPS was adjusted to 0.

92 yuan (the original predictor variable is 0.

96 yuan), 1.

21 yuan (the original predictor 1).

22 yuan), 1.

60 yuan (the original predictor variable 1).
58 yuan), PE corresponding to the closing price on November 1 were about 34.
6, 26.

5, 20.

0 times.

The company is a leading company in the national e-government industry, benefiting from the continued growth of the domestic e-government market, and the company’s e-government business has a solid foundation.

Adhering to its leading advantages in the field of e-government, the company has a good development momentum in the field of government cloud.

The company is one of the best system integrators in developing countries. As the overall unit of China Electronics Technology Group’s autonomous and controllable industry, the company maximizes its autonomous and controllable ecology and has ample future development space for autonomous and controllable business.

We are optimistic about the company’s future development and maintain a “recommended” rating on the company.

Risk reminders: (1) The growth rate of e-government business is not up to expectations: The growth of the domestic e-government industry market size is greatly affected by government investment in informatization construction. If the government’s expenditure on informatization construction changes,There is a risk that the market scale of the domestic e-government industry will exceed expectations, and the company’s e-government business will have a risk of not growing as expected; (2) The progress of cloud service business promotion is not as expected: the company’s government cloud business includes Beijing Municipal Affairs CloudHainan Government Affairs Cloud, Shanxi Province Government Affairs Cloud and other benchmark customers. In March 2019, the company successfully won the Tianjin Municipal Affairs Cloud.

If the company’s government affairs cloud business cannot continue to promote the application scope and application depth on existing projects, or the development of new projects fails to meet expectations, the company’s cloud service business may not meet the expected expansion schedule; (3) autonomouslyControl business development is not up to expectations: At present, domestic basic software and hardware platforms have been basically available, but the ecological shortage is serious. The adaptation between basic software and hardware products (CPU, operating system, database, etc.) is facing challenges.

The company is backed by China Electronics Technology Group. 南宁桑拿 Although it is relatively perfect in ecological construction, if the adaptive solution cannot be continuously improved, or the user experience of the introduced adaptive solution is not up to expectations, the company’s autonomous and controllable business may not develop as expected.risks of.

Zhibang Home (603801): Wardrobe bulk drives revenue to accelerate profitability remains stable

Zhibang Home (603801): Wardrobe bulk drives revenue to accelerate profitability remains stable

Event: The company announced the third quarter report of 2019 and realized operating income from January to September.

600 million, an annual increase of 12.

9%, net profit attributable to mother 2.

3 ppm, an increase of 14 per year.

5%, after deducting non-return to mother’s net profit increased by 9%.

9%.

One single Q3 realized income 8.

1 billion, an increase of 16 a year.

9%; net profit attributable to mother 1.

2.3 billion, an annual increase of 13.

1%.

Comments: 1. Revenue growth is accelerating month-on-month, wardrobe and bulk business maintain rapid growth, and retail channels are relatively stable. Q3 single-quarter revenue is +16 per year.

9%, 3% faster than the previous month.

6 points.

In terms of categories, the growth of kitchen cabinets (accounting for about 70%) is basically the same as last year, and wardrobes (accounting for about 25%) increased by 70-80%. In terms of distribution channels, cabinets 深圳spa会所 in distribution channels have a small order of magnitude, and engineering channels (proportion(About 18%) in the first three quarters of about 35%.

Wardrobes and bulk businesses are the main drivers of the company’s growth.

In terms of channel expansion, there were 1,567 cabinet stores at the end of Q3, a net increase of 80; 978 wardrobe stores, a net increase of 252; and more than 100 wooden doors.

In addition, the unit price of cabinets and closets is expected to be basically stable at around 1 million.

2. The scale effect led to a slight increase in gross profit margin, stable profitability, and significant improvement in cash flow reduction. Q3 Comprehensive gross profit margin was 40%, an increase of 1.

5 points.

In 19, the company’s wardrobe was converted, the scale of the wooden door business further expanded, and the profit optimization of the bulk business still contributed to the overall gross profit margin.

In terms of expenses, the sales expenses are at least + 2pct, which is mainly due to the increase in marketing activities and advertising expenses. In addition, the rapid growth of major businesses has led to the increase in service expenses. It is expected that the effect of some expenses will be realized in the fourth quarter. The overall expenditure rate is controllable and profitable.Capability remains stable.

In terms of cash flow, Q3 net operating cash inflow was zero.

84 yuan, at least a significant improvement, although accounts receivable and bills increased by 1.

300 million, but accounts payable and bills increased by 1.

200 million, advance receipts increased by 0 in ten years.

600 million, the company’s bargaining power in the industry chain is increasing.

3. The large-scale increase in revenue has led to the gradual significant effect of the coordinated development of cabinet wood. Maintaining the “Highly Recommended-A” rating. As the penetration rate of hardcover rooms gradually increases, the company’s large-scale business drives the company’s stable and rapid growth.

In addition, we continue to be optimistic about the company’s “1 + 1 + 4” development strategy of “big customization + leading design + strong terminals, supply chain, digitalization, and talent”: 1) category expansion, kitchen clothes, wood linkage, and whole house customization to increase customer unit prices; 2)Expansion of the channel optimizes the structure and focuses on quality, and explores the installation and Internet home improvement channels; 3) Equity cooperation model is established, and internal incentives are in place; 4) Invest in Australian kitchen cabinet manufacturer IJF, and start the overseas investment chapter.

Expected 2019?
The net profit attributable to mothers will be 3 in 2021.

1.4 billion, 3.

6.3 billion, 4.

32 trillion US dollars, an annual increase of 15%, 16%, 19%. At present, the corresponding 19-year PE is 15x, maintaining the “strongly recommended-A” rating.

Risk warning: industry competition is intensifying, and the completion data is not up to expectations.

Hengrui Medicine (600276): Phase 1 clinical trial of PD-1 esophageal cancer reaches primary endpoint

Hengrui Medicine (600276): Phase 1 clinical trial of PD-1 esophageal cancer reaches primary endpoint

Company dynamics keep outperforming the industry. Hengrui has announced that the company ‘s PD-1 drug, Carelizumab, for multi-center Phase 3 clinical studies (ESCORT) in the treatment of advanced esophageal cancer has reached its primary endpoint (overall survival).

ESCORT studies have shown that for patients with locally advanced or metastatic esophageal cancer who have failed previous first-line chemotherapy, receiving carelizumab versus chemotherapy chosen by the investigator can prolong the overall survival of the patient.

  Comment on the benchmark chemotherapy reached the primary endpoint, detailed data to be further disclosed.

The ESCORT study was led by Professor Xu Jianming of the Fifth Medical Center of the General Hospital of the Chinese People’s Liberation Army and Professor Huang Jing of the Cancer Hospital of Chinese Academy of Medical Sciences.

The study began in May 2017. Until May 2019, a total of 448 patients were enrolled, of which 228 received carelizumab and 220 received chemotherapy.

Recent studies have reached the primary preliminary study endpoint of overall survival.

The company plans to publish detailed research data at Xiamen CSCO and Barcelona ESMO in September 2019.

  The esophageal cancer market has huge potential.

Esophageal cancer is a chronic, high-incidence cancer type, with an annual incidence of close to 500,000 patients, which is different from the adenocarcinoma in Europe and the United States, so more than 90% are squamous cell carcinoma.

At present, chemotherapy for first-line drugs for esophageal cancer is still the gold standard. Patients who enter the second-line after first-line treatment of complications often still use chemotherapy, and alternative treatment options are still available.

This time, Hengrui achieved the main endpoint in the second-line treatment of advanced chemotherapy for advanced esophageal cancer, progressing to the first in China.

Considering that there are huge unmet clinical needs in the current market and Hengrui’s leading progress in this indication, we are optimistic about the sales potential of the company PD-1 in esophageal cancer.

  The company’s combined chemotherapy for first-line treatment of esophageal cancer is also expected, and preliminary results are expected in 2020.

  The company expects to submit NDA in the second half of the year, becoming the third indication.

Following Hodgkin’s lymphoma approval 杭州夜网 for marketing, Hengrui’s second-line treatment for hepatocellular carcinoma has applied for conditional approval for marketing.

The company plans to submit NDA for esophageal cancer indications in the second half of 2019, which will become the third indication for listing.

Considering the company’s leading progress in large indications and outstanding sales capabilities, we believe that Hengrui is expected to eventually replace the largest market share of domestic PD-1.

We will also pay close attention to the follow-up progress of the company PD-1.

  Estimates suggest that we maintain EPS 1 for 2019/2020.

22 yuan / 1.

49 yuan unchanged, the previous growth was 33.

2% / 22.

0%, the company’s current sustainable corresponding 19/20 P / E is 54.

3X / 44.

5 times.

  We maintain our Outperform rating and target 深圳桑拿网 price of 73.

3 yuan unchanged (corresponding to the current remaining 10.
.

2% upside), the target price corresponding to 2019/20 PE is 60X / 49X.

  Risks The development of major PD-1 indications has fallen short of expectations; drug sales have fallen short of expectations.

Two weight loss recipes for plow and apple women

Two weight loss recipes for plow and apple women

To lose weight, you must choose the right weight loss aspect according to your specific type. Weight loss recipes are no exception. Today, the weight loss recipes network will introduce you to the weight loss recipes of two types of pears and apples.To help you lose weight quickly!

The following is the detailed content provided by Xiaobian.com. People who eat pears like pears are fried chicken, cakes, potato chips, ice cream and other high-fat foods, and apple-like sweets.In the rankings, all the adult-style sweets with a high content of adults.

Other fried items like fried rice, fried noodles or french fries are also pear-shaped favorites!

  Pear-type diet strategies must minimize fat intake, and the amount of staple food need not be deliberately reduced!

  OK Food Vegetables, Mushrooms, Fish and Shellfish, White Meat, Rice, Pasta NG Food Fried Chicken, Red Meat, Cream, Mayonnaise, Traces of High Snack Chef Suggestion.

Be careful not to eat too much fat. When preparing food, try using a pan or non-stick pan, and slide the oil over the entire surface of the pan. Try to use only a little oil when cooking.Slow-frying over low heat, so lightly brings out the sweetness and aroma of the vegetables themselves!

  Stay away from fried foods, use steamed stews, or grill instead of fried.

Maybe people who eat as usual can choose to marinate, instead of fried chicken legs or fried pork ribs.

Foods that are too greasy, remember to suck oil or boil it after boiling water.

  2.

Pick as much white meat as possible, lean meat pear style eat meat, and like muscle, ground meat, pork belly and other oil-rich parts.

  Pear-type people are advised to choose thinner parts when eating meat, especially white meat such as chicken and fish should be used instead of red meat such as pork and beef, especially when eating chicken, peel and eat.

  Apple-type Apple-type people like to eat foods such as cereals and potatoes with appropriate sugar content, such as buns, rice, taro, candy, etc., and also like beer and wine.

  The perception of eating is “even if there is no side dish, eating rice is willing.”

  The apple-type diet strategy is to eat half of the staple rice with noodles, and fill the stomach with vegetables and protein for the rest!

  OK Food Vegetables, Mushrooms, Fish and Shellfish, Tofu, Low Fat Yogurt NG Food Rice, Noodles, Taro, Pumpkin, Sweets, Juice Chef Suggestion 1.

Let’s eat some lettuce salad or hot vegetables before meals!

  Apple-type people’s focus on weight loss is “how to reduce staple food and still feel full.”

Before eating dinner, you can eat hot vegetables or lettuce salad, you can eat less rice 白!

  2.

Not full?

Endure for 20 minutes!

  People who eat too fast can easily eat too much food before they feel full!

  First of all, you must chew slowly and slowly. You can substitute rice with rice or grain rice.

If one bowl is not enough, it is recommended that you endure for 20 minutes, and wait for the nerve center that controls satiety to start moving!

  3.

If waiting for 20 minutes is not enough.
If your mouth is sloppy, it is recommended to drink a large glass of water to fill your stomach before eating, or eat vegetables such as gherkin, parsley, white radish, carrot, etc., which can be chewed slowly.

What to eat for gout

What to eat for gout

There are many rumors about food that gout patients cannot eat, such as “cannot eat beer and seafood together”, “cannot eat soy products”, “cannot drink hot pot soup”, “cannot drink sweet drinks” and so on.

These rumors, what is true and false, what are the taboos on the diet of gout patients?

  Gout is closely related to uric acid.

The human body produces purines, and purines are supplemented from food. Purine metabolism produces uric acid, which is normally excreted from the urine through the veins.

But if there are too many purines, a lot of uric acid will be produced.

Too much uric acid, or poor access to uric acid, will accumulate in the body.

When accumulated to a certain concentration, uric acid crystals will precipitate, which will cause gout.

  People do not easily change the purines produced in the body, but can avoid high-purity purine foods to reduce uric acid production.

Among the common foods in Chinese, animal water is the highest purine species, such as liver, waist, heart, brain, plasma, etc.

In addition, game, goose, certain fish (such as sardines, herring, salmon, etc.), scallops, etc. are also in this category.

One hundred grams of these foods usually contains more than 200 milligrams of purine.

Basically all kinds of meat, some pork, beef, lamb, aquatic products, etc., usually contain 100 to 200 mg of purine per 100 grams.

There are also trace amounts of purine in dried soybeans, but the content can only be low after adding soy products. It is similar to oatmeal, broccoli, peas, spinach, green peppers, bananas and other vegetables and fruits.

  Although alcohol and sugar are not rich in purines, they will affect uric acid metabolism and increase the uric acid content in the blood, so gout patients should also avoid it.

  In the widespread taboos of gout diet, whether seafood and beer are eaten together or separately, they are high-risk factors, such as “cannot eat arsenic and dichlorvos together”; “cannot eat soy products” is contrary to scientific evidence, epidemiologyThe survey found that soy products and other vegetables and fruits with a “higher” purine content did not increase the uric acid content in the blood. Some surveys even showed that the blood uric acid content was increased in people with high consumption of soy products; sugary drinksIncreasing blood uric acid is supported by scientific evidence; usually hot pot soup will contain excessive purines, which should be avoided by gout patients.

  In summary, the dietary principles of gout patients (or people with high uric acid) can be briefly described as follows: Avoid various animal internal organs, brain, game, certain seafood and fish, beer and other alcoholic beverages, (although not all seafood andFishes contain high-purity purines, but if you count them clearly, avoid them); Control high-sugar foods, polished rice noodles, saturated traces, and various meats; recommended coarse grains, whole grains, etc., low-fat and fat-freeDairy products, vegetable protein foods, lots of water.

Mother’s Declaration of Beauty

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Mother’s Declaration of Beauty

Ms. Xie, 26, has been practicing yoga here for almost 3 months. “I have been practicing yoga for more than 5 months with my baby.

“When this expectant mother who always loves sports first went to the gym, the elders didn’t support it. The husband gave her absolute support. Yoga sessions several times a week will always accompany her as long as her husband is free.

  ”When she started to sign up, we were also hesitant. We decided to accept her to exercise after many communication with the yoga instructor.

Talking about the first mother-to-be book that has been accepted since its opening, the staff of Tiantian Fitness Club told reporters that in order to meet the requirements of the book, the club will make arrangements based on the actual situation of the book.Ms. reduced “emphasis protection”.

Evening is the timetable with the most scholars. The air is relatively stagnant. For health reasons, Ms. Xie was suggested to attend the afternoon class. The coach also drew a diagram of yoga exercises suitable for pregnant women.

  ”Pregnant women actually need to reduce their perception of old age, and they will be released well if they exercise properly.

“At this moment, the expectant mother, who had just finished her exercise, made this remark, and she looked rosy and beautiful.